A review of the studies of the cardiovascular health effects of methylmercury with consideration of their suitability for risk assessment. Homan van der Heide JJ, Bilo, H. J., Tegzess, A. M., and Donker, A. J. 2011;17(1):336-345. Moderate intake of n-3 fatty acids for 2 months has no detrimental effect on glucose metabolism and could ameliorate the lipid profile in type 2 diabetic men. Prostaglandins 1980;20(6):1021-1031. Reliant Pharmaceuticals. Marine omega-3 fatty acid intake and survival of stage III colon cancer according to tumor molecular markers in NCCTG Phase III trial N0147 (Alliance). 2009;57(8):1481-1486. 7-26-2012;367(4):309-318. Long-term effects of n-3 fatty acids on serum lipids and glycaemic control. Available at: https://www.cfsan.fda.gov/~frf/sea-mehg.html. Fish oil supplemented for 9 months does not improve glycaemic control or insulin sensitivity in subjects with impaired glucose regulation: a parallel randomised controlled trial. Atherosclerosis 1998;140(1):181-186. J Ren Nutr 2005;15(2):253-256. Campbell F, Dickinson HO, Critchley JA, Ford GA, Bradburn M. A systematic review of fish-oil supplements for the prevention and treatment of hypertension. 2018;57(7):2387-2397. View abstract. Gura, K. M., Duggan, C. P., Collier, S. B., Jennings, R. W., Folkman, J., Bistrian, B. R., and Puder, M. Reversal of parenteral nutrition-associated liver disease in two infants with short bowel syndrome using parenteral fish oil: implications for future management. Brouwer, I. Mallah, H. S., Brown, M. R., Rossi, T. M., and Block, R. C. Parenteral fish oil-associated burr cell anemia. This survey is being conducted by the WebMD marketing sciences department. View abstract. View abstract. View abstract. 4-1-2008;47(4):459-466. View abstract. Circulation 2005;112:1945-52. Maffettone A. Fish oil supplements are often cited as one of the best ways to maintain and improve heart health but studies show that it does not really have a major effect in individuals who actually have risk factors associated with heart disease. View abstract. Bougle, D., Denise, P., Vimard, F., Nouvelot, A., Penneillo, M. J., and Guillois, B. Circulation 2003;108:820-5.. View abstract. J.Clin.Psychiatry 2012;73(9):1245-1254. Clin Allergy 1988;18(2):177-187. Am Heart J 143:E5. Fewtrell, M. S., Morley, R., Abbott, R. A., Singhal, A., Isaacs, E. B., Stephenson, T., MacFadyen, U., and Lucas, A. Double-blind, randomized trial of long-chain polyunsaturated fatty acid supplementation in formula fed to preterm infants. Psychiatr.Clin North Am 2000;23(4):785-794. 2012;107 Suppl 2:S228-S239. Colon cancer, rectal cancer. Sekine, K. Hepatic role in the storage and utilization of fish oil fatty acids in humans: studies on liver surgery patients. Clin Nutr 1998;17:265-271. Baro, L., Fonolla, J., Pena, J. L., Martinez-Ferez, A., Lucena, A., Jimenez, J., Boza, J. J., and Lopez-Huertas, E. n-3 Fatty acids plus oleic acid and vitamin supplemented milk consumption reduces total and LDL cholesterol, homocysteine and levels of endothelial adhesion molecules in healthy humans. View abstract. Eur J Clin Nutr 2007;61(3):314-325. Kujur SK, Goswami V, Nikunj AM, Singh G, Bandhe S, Ghritlahre H. Efficacy of omega 3 fatty acid as an adjunct in the management of chronic periodontitis: A randomized controlled trial. Grundt, H., Nilsen, D. W., Mansoor, M. A., Hetland, O., and Nordoy, A. Tomiyama, H., Takazawa, K., Osa, S., Hirose, K., Hirai, A., Iketani, T., Monden, M., Sanoyama, K., and Yamashina, A. Bergmann, R. L., Haschke-Becher, E., Klassen-Wigger, P., Bergmann, K. E., Richter, R., Dudenhausen, J. W., Grathwohl, D., and Haschke, F. Supplementation with 200 mg/day docosahexaenoic acid from mid-pregnancy through lactation improves the docosahexaenoic acid status of mothers with a habitually low fish intake and of their infants. Nemets, H., Nemets, B., Apter, A., Bracha, Z., and Belmaker, R. H. Omega-3 treatment of childhood depression: a controlled, double-blind pilot study. Fish oil supplements have become increasingly popular due to the heart-healthy benefits of omega-3 fatty acids present in the fish oil itself. Clin.Nutr. Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma: a double-blind, randomized, placebo-controlled study. Fish oil and plasma fibrinogen. Facts & Comparisons eAnswers. Atherosclerosis 2008;197(2):821-828. Circulation 2003;108:1. 2020;99(19):e20119. Meshcheriakova, V. A., Plotnikova, O. A meta-analysis. View abstract. Curr.Opin.Psychiatry 2012;25(1):52-58. Fish intake and risk of incident atrial fibrillation. Eur.J.Clin.Nutr. Lucas A, Stafford M Morley R Abbott R Stephenson T MacFadyen U Elias-Jones A Clements H. Efficacy and safety of long-chain polyunsaturated fatty acid supplementation of infant-formula milk: a randomised trial. View abstract. Bath-Hextall, F. J., Jenkinson, C., Humphreys, R., and Williams, H. C. Dietary supplements for established atopic eczema. View abstract. View abstract. Lipids 1992;27(11):901-907. Research into the effects of fish oil on Crohn disease has produced conflicting results. Moderate fish-oil supplementation reverses low-platelet, long-chain n-3 polyunsaturated fatty acid status and reduces plasma triacylglycerol concentrations in British Indo-Asians. These conditions can be improved by improving blood flow, which omega-3 fatty acids in the blood stream. Effect of a protein and energy dense n-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial. The acute and short-time effect of supplementation with the combination of n-3 fatty acids and acetylsalicylic acid on platelet function and plasma lipids. Arch Gen Psychiatry 2002;59:913-9.. View abstract. Europace. World J.Gastroenterol. Fortin PR, Lew RA, Liang MH, et al. The effects of dietary supplementation with fish oil on renal function in cyclosporine-treated renal transplant recipients. View abstract. Gogos, C. A., Ginopoulos, P., Salsa, B., Apostolidou, E., Zoumbos, N. C., and Kalfarentzos, F. Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: a randomized control trial. View abstract. Zeman, M., Zak, A., Vecka, M., Tvrzicka, E., Pisarikova, A., and Stankova, B. N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination. Age-Related Eye Disease Study 2 Research Group. View abstract. Toft I, Bonaa KH, Ingebretsen OC, et al. View abstract. PLoS.One. Kurlandsky, L. E., Bennink, M. R., Webb, P. M., Ulrich, P. J., and Baer, L. J. Connor WE, Connor SL. 2004;26(4):453-459. 12 Many speculate that the benefits of fish oil supplements were over-exaggerated in earl studies. 2018 Oct 18;379(16):1540-1550. Lancet 9-22-1984;2(8404):696-697. The essential extracts of the Omega-3 Fatty acids –DHA and EPA are skillfully preserved in the oil extracts. Associations of omega-3 fatty acid supplement use with cardiovascular disease risks: Meta-analysis of 10 trials involving 77?917 individuals. J Nutr 2003;133:2210-3.. View abstract. Peters, B. S., Wierzbicki, A. S., Moyle, G., Nair, D., and Brockmeyer, N. The effect of a 12-week course of omega-3 polyunsaturated fatty acids on lipid parameters in hypertriglyceridemic adult HIV-infected patients undergoing HAART: a randomized, placebo-controlled pilot trial. Dietary sources of DHA and EPA are fatty fish, such as salmon, mackerel and trout, and shellfish, such as mussels, oysters and crabs. Sala-Vila A, Díaz-López A, Valls-Pedret C, et al. Acta Med.Scand.Suppl 1966;466:1-92. Three-year outcomes of dietary fatty acid modification and house dust mite reduction in the Childhood Asthma Prevention Study. But higher quality research suggests that taking fish oil does not have this effect. Arterioscler.Thromb.Vasc Biol 1997;17(5):814-819. Am J Clin Nutr 2009;90(6):1601-1607. Vidgren, H. M., Agren, J. J., Schwab, U., Rissanen, T., Hanninen, O., and Uusitupa, M. I. Incorporation of n-3 fatty acids into plasma lipid fractions, and erythrocyte membranes and platelets during dietary supplementation with fish, fish oil, and docosahexaenoic acid-rich oil among healthy young men. J Hypertens 2004;22:921-9. View abstract. View abstract. A controlled double-blind trial. View abstract. Caniato, R. N., Alvarenga, M. E., and Garcia-Alcaraz, M. A. 11-7-2008;14(41):6395-6400. Fassett, R. G., Gobe, G. C., Peake, J. M., and Coombes, J. S. Omega-3 polyunsaturated fatty acids in the treatment of kidney disease. Treatment of IgA nephropathy with omega-3-polyunsaturated fatty acids: a prospective, double-blind, randomized study. 2007;86(6):1670-1679. Omega-3 polyunsaturated fatty acids are found in oils from certain types of fish, vegetables, and other plant sources. Harper, M., Thom, E., Klebanoff, M. A., Thorp, J., Jr., Sorokin, Y., Varner, M. W., Wapner, R. J., Caritis, S. N., Iams, J. D., Carpenter, M. W., Peaceman, A. M., Mercer, B. M., Sciscione, A., Rouse, D. J., Ramin, S. M., and Anderson, G. D. Omega-3 fatty acid supplementation to prevent recurrent preterm birth: a randomized controlled trial. Fish oil supplementation improves pregnancy outcomes and size of the newborn: a meta-analysis of 21 randomized controlled trials. Acta Paediatr. Nutr.Clin.Pract. Sanders, T. A., Gleason, K., Griffin, B., and Miller, G. J. Eur J Clin Nutr. A., Molony, D. A., and Strippoli, G. F. Non-immunosuppressive treatment for IgA nephropathy. View abstract. Eur.J.Clin.Nutr. April 16, 2004. Annu Sci Meet Thorac Soc 1997;1. Effect of Supplementation with Polyunsaturated Fatty Acids and Micronutrients on Learning and Behavior Problems Associated with Child ADHD. Kairaluoma, L., Narhi, V., Ahonen, T., Westerholm, J., and Aro, M. Do fatty acids help in overcoming reading difficulties? JAMA 1988;260:665-70. Improvement in the plasma omega-3 index by the use of a fish oil-enriched spread. Prostaglandins Leukot.Essent.Fatty Acids 2007;77(2):105-107. View abstract. Bent, S., Bertoglio, K., and Hendren, R. L. Omega-3 fatty acids for autistic spectrum disorder: a systematic review. Dewailly E, Blanchet C, Gingras S, et al. Chalon, S. Omega-3 fatty acids and monoamine neurotransmission. FDA. View abstract. View abstract. Richardson AJ, Puri BK. Am.J.Clin.Nutr. View abstract. Geleijnse, J. M., Giltay, E. J., and Kromhout, D. Effects of n-3 fatty acids on cognitive decline: a randomized, double-blind, placebo-controlled trial in stable myocardial infarction patients. Ozaydin, M., Erdogan, D., Tayyar, S., Uysal, B. Harris, W. S., Reid, K. J., Sands, S. A., and Spertus, J. View abstract. Finnegan YE, Minihane AM, Leigh-Firbank EC, et al. View abstract. DeFilippis, A. P., Harper, C. R., Cotsonis, G. A., and Jacobson, T. A. Circulation 3-4-2008;117(9):1130-1137. View abstract. View abstract. Eur J Cancer Prev 1995;4(4):329-332. Fortier, M., Tremblay-Mercier, J., Plourde, M., Chouinard-Watkins, R., Vandal, M., Pifferi, F., Freemantle, E., and Cunnane, S. C. Higher plasma n-3 fatty acid status in the moderately healthy elderly in southern Quebec: higher fish intake or aging-related change in n-3 fatty acid metabolism? Int J Cardiol 2005;100:461-6. Circulation 1-15-1996;93(2):365-371. Harel Z, Gascon G, Riggs S, et al. Arch.Gen.Psychiatry 1999;56(5):413-414. Ascherio A, Rimm EB, Stampfer MJ, et al. In people with type 2 diabetes, some research shows that taking fish oil might help kidney function. Geusens, P., Wouters, C., Nijs, J., Jiang, Y., and Dequeker, J. View abstract. Freese R, Mutanen M. Alpha-linolenic acid and marine long-chain n-3 fatty acids differ only slightly in their effects on hemostatic factors in healthy subjects. Harper, C. R. and Jacobson, T. A. View abstract. Espersen, G. T., Grunnet, N., Lervang, H. H., Nielsen, G. L., Thomsen, B. S., Faarvang, K. L., Dyerberg, J., and Ernst, E. Decreased interleukin-1 beta levels in plasma from rheumatoid arthritis patients after dietary supplementation with n-3 polyunsaturated fatty acids. Research shows that taking fish oil, alone or with vitamin B12 or vitamin E, can improve painful periods and reduce the need for pain medications in women with menstrual cramps. Am J Clin Nutr 2009;90(1):170-176. Clinical research is inconsistent. Toft, I., Bonaa, K. H., Ingebretsen, O. C., Nordoy, A., and Jenssen, T. Fibrinolytic function after dietary supplementation with omega3 polyunsaturated fatty acids. Effects of an open-label pilot study with high-dose EPA/DHA concentrates on plasma phospholipids and behavior in children with attention deficit hyperactivity disorder. 2017;7(12):1. 1994;8(1):43-49. Atherosclerosis 1990;84(2-3):229-237. Green, P., Fuchs, J., Schoenfeld, N., Leibovici, L., Lurie, Y., Beigel, Y., Rotenberg, Z., Mamet, R., and Budowski, P. Effects of fish-oil ingestion on cardiovascular risk factors in hyperlipidemic subjects in Israel: a randomized, double-blind crossover study. 9-16-2008;52(12):988-996. Taking fish oil or eating seafood during pregnancy might help prevent premature delivery. B., and Ingebretsen, O. C. Effects of Simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidaemia. View abstract. View abstract. Pandalai, P. K., Pilat, M. J., Yamazaki, K., Naik, H., and Pienta, K. J. Lauritzen, L., Kjaer, T. M., Fruekilde, M. B., Michaelsen, K. F., and Frokiaer, H. Fish oil supplementation of lactating mothers affects cytokine production in 2 1/2-year-old children. JPEN J Parenter.Enteral Nutr 1998;22(4):206-211. (Lond) 2008;32(7):1105-1112. J Nutr 2008;138(1):30-35. One-year treatment with ethyl esters of n-3 fatty acids in patients with hypertriglyceridemia and glucose intolerance: reduced triglyceridemia, total cholesterol and increased HDL-C without glycemic alterations. Historical overview of n-3 fatty acids and coronary heart disease. J.Am.Coll.Nutr. Arterioscler.Thromb. View abstract. Am J Clin Nutr 2006;83(6 Suppl):1467S-1476S. Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acid. View abstract. Conklin, S. M., Manuck, S. B., Yao, J. K., Flory, J. D., Hibbeln, J. R., and Muldoon, M. F. High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism. Gut 2003;52(10):1479-1486. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Fewtrell MS, Abbott RA, Kennedy K, et al. Prostaglandins Leukot.Essent.Fatty Acids 2005;72(3):211-218. Miller PE, Van Elswyk M, Alexander DD. Bowden, R. G., Wilson, R. L., Deike, E., and Gentile, M. Fish oil supplementation lowers C-reactive protein levels independent of triglyceride reduction in patients with end-stage renal disease. Results of a controlled study. Hay fever. View abstract. Gianotti, L., Braga, M., Vignali, A., Balzano, G., Zerbi, A., Bisagni, P., and Di, Carlo, V. Effect of route of delivery and formulation of postoperative nutritional support in patients undergoing major operations for malignant neoplasms. Pediatr Res 1990;28(5):485-492. 2009 Apr 1;15(7):2559-66. n-3 fatty acid supplementation for the treatment of dry eye disease. But it doesn't seem to reduce the chance of death from other causes. Omega-3 fatty acids (natural products database). Safety and efficacy of omega-3 fatty acids in the nutrition of very low birth weight infants: soy oil and marine oil supplementation of formula. View abstract. But other research shows that taking fish oil for 11 months delays the development of the condition. 2019 Jun 26;6:CD012815. The role of n-3 fatty acids in visual and cognitive development: current evidence and methods of assessment. Mimoun, M., Coste, T. C., Lebacq, J., Lebecque, P., Wallemacq, P., Leal, T., and Armand, M. Increased tissue arachidonic acid and reduced linoleic acid in a mouse model of cystic fibrosis are reversed by supplemental glycerophospholipids enriched in docosahexaenoic acid. A docosahexaenoic acid-functional food during pregnancy benefits infant visual acuity at four but not six months of age. Calder PC. Usefulness of omega-3 fatty acids and the prevention of coronary heart disease. Makrides M, Best K, Yelland L, et al. Arm, J. P., Horton, C. E., Mencia-Huerta, J. M., House, F., Eiser, N. M., Clark, T. J., Spur, B. W., and Lee, T. H. Effect of dietary supplementation with fish oil lipids on mild asthma. View abstract. Kim, J., Lim, S. Y., Shin, A., Sung, M. K., Ro, J., Kang, H. S., Lee, K. S., Kim, S. W., and Lee, E. S. Fatty fish and fish omega-3 fatty acid intakes decrease the breast cancer risk: a case-control study. While generally safe, getting too much fish oil can increase your risk of bleeding and might affect your immune response. Kalmijn, S., Launer, L. J., Ott, A., Witteman, J. C., Hofman, A., and Breteler, M. M. Dietary fat intake and the risk of incident dementia in the Rotterdam Study. Swails, W. S., Kenler, A. S., Driscoll, D. F., DeMichele, S. J., Babineau, T. J., Utsunamiya, T., Chavali, S., Forse, R. A., and Bistrian, B. R. Effect of a fish oil structured lipid-based diet on prostaglandin release from mononuclear cells in cancer patients after surgery. Effect of diets high in omega-3 and omega-6 fatty acids on initiation and postinitiation stages of colon carcinogenesis. 2011;18(22):3322-3329. 11-1-2001;154(9):809-816. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. B., and Beilin, L. J. Biol.Psychiatry 2-15-2007;61(4):551-553. Modulation of lipid profile by fish oil and garlic combination. View abstract. View abstract. Atherosclerosis 2003;166(1):85-93. Therapeutic effects of docosahexaenoic acid ethyl ester in patients with generalized peroxisomal disorders. J Rheumatol 2000;27:298-303. Supplementation with omega-3 fish oil has no effect on bone mineral density in adults with knee osteoarthritis: a 2-year randomized controlled trial. JAMA 1-7-1998;279(1):23-28. View abstract. 2012;1(3):e000547. View abstract. View abstract. Lancet 1999;354:447-55. Food Funct 2013;4(4):650-8. US Environmental Protection Agency. Bosch, J., Gerstein, H. C., Dagenais, G. R., Diaz, R., Dyal, L., Jung, H., Maggiono, A. P., Probstfield, J., Ramachandran, A., Riddle, M. C., Ryden, L. E., and Yusuf, S. n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. View abstract. Other research shows that applying fish oil to the heels of hospitalized adults does not reduce the risk of getting a bed sore on the heel. View abstract. Lipids 1989;24(4):290-295. Hill AM, Buckley JD, Murphy KJ, Howe PR. Aguila MB, Pinheiro AR, Mandarim-de-Lacerda CA. View abstract. Shapiro, J. View abstract. View abstract. Fish oil (Eicosapen) is less effective than metronidazole, in combination with pantoprazole and clarithromycin, for Helicobacter pylori eradication. Circulation. Br J Cancer 1999;81:1238-42. View abstract. A cohort study. An oral supplement enriched with fish oil, soluble fiber, and antioxidants for corticosteroid sparing in ulcerative colitis: a randomized, controlled trial. https://www.uptodate.com/contents/search. Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. View abstract. View abstract. Consumption of oily fish and childhood asthma risk. Shah, A. P., Ichiuji, A. M., Han, J. K., Traina, M., El-Bialy, A., Meymandi, S. K., and Wachsner, R. Y. Cardiovascular and endothelial effects of fish oil supplementation in healthy volunteers. Skulas-Ray AC, Wilson PWF, Harris WS, et al. Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Best KP, Sullivan T, Palmer D, et al. Stanke-Labesque, F., Moliere, P., Bessard, J., Laville, M., Vericel, E., and Lagarde, M. Effect of dietary supplementation with increasing doses of docosahexaenoic acid on neutrophil lipid composition and leukotriene production in human healthy volunteers. 2004;24(5):474-482. Although fish is an excellent source of dietary protein, choosing fish oil supplements instead is appropriate in some cases. View abstract. 2018;21(9):614-623. Med Sci Sports Exerc 2002;34:1605-13. J Allergy Clin Immunol 1989;83:196. View abstract. Nestel PJ. Seidner DL, Lashner BA, Brzezinski A, et al. Manson JE, Cook NR, Lee IM, et al. Barberger-Gateau, P., Raffaitin, C., Letenneur, L., Berr, C., Tzourio, C., Dartigues, J. F., and Alperovitch, A. Dietary patterns and risk of dementia: the Three-City cohort study. Early dietary treatments with Lorenzo's oil and docosahexaenoic acid for neurological development in a case with Zellweger syndrome. The clinical effect of dietary supplementation with omega-3 fish oils and/or copper in systemic lupus erythematosus. Morgan, W. A., Raskin, P., and Rosenstock, J. View abstract. 2017;29(12):791-801. Rose, D. P. and Connolly, J. M. Omega-3 fatty acids as cancer chemopreventive agents. Kwak SM, Myung SK, Lee YJ, Seo HG. Pediatr.Allergy Immunol. Guallar, E., Hennekens, C. H., Sacks, F. M., Willett, W. C., and Stampfer, M. J. Gutstein AS, Copple T. Cardiovascular disease and omega-3s: Prescription products and fish oil dietary supplements are not the same. Omega-3 fatty acids in cardiovascular care. View abstract. Vopr.Pitan. Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury. Ann.Surg. 9-29-1989;62(2):797-801. JAMA Netw Open. Effects of marine fish oils on the anticoagulation status of patients receiving chronic warfarin therapy. Effects of omega-3 fatty acids on child and maternal health. Siscovick DS, Barringer TA, Fretts AM, et al. (abstract) J Am Coll Cardiol 2000;35:265-70. View abstract. de Lorgeril M, Renaud S, Mamelle N, et al. J Clin Psychiatry 2005;66(6):726-729. View abstract. View abstract. View abstract. Virtanen, JK Mursu J Voutilainen S Tuomainen TP. Dietary fish oil effects on seasonal hay fever and asthma in pollen- sensitive subjects. But taking fish oil might provide some other benefits for people with diabetes. A few more thoughts about fish and fish oil. View abstract. View abstract. 2001;28(8):769-774. J Am Coll Nutr 2009;28(5):525-542. Medications for high blood pressure (Antihypertensive drugs) interacts with FISH OIL. 2009;60 Suppl 5:136-142. J.Am.Coll.Cardiol. View abstract. Clin.Nutr. Active rheumatoid arthritis: effect of dietary supplementation with omega-3 oils. View abstract. View abstract. But taking fish oil by mouth does not seem to have any effect on psoriasis. View abstract. Lim, W. S., Gammack, J. K., Van, Niekerk J., and Dangour, A. D. Omega 3 fatty acid for the prevention of dementia. View abstract. View abstract. Onwude JL, Lilford RJ, Hjartardottir H, et al. Macchia, A., Levantesi, G., Franzosi, M. G., Geraci, E., Maggioni, A. P., Marfisi, R., Nicolosi, G. L., Schweiger, C., Tavazzi, L., Tognoni, G., Valagussa, F., and Marchioli, R. Left ventricular systolic dysfunction, total mortality, and sudden death in patients with myocardial infarction treated with n-3 polyunsaturated fatty acids. Roman, A. S., Schreher, J., Mackenzie, A. P., and Nathanielsz, P. W. Omega-3 fatty acids and decidual cell prostaglandin production in response to the inflammatory cytokine IL-1beta. Kaul, U., Sanghvi, S., Bahl, V. K., Dev, V., and Wasir, H. S. Fish oil supplements for prevention of restenosis after coronary angioplasty. Nordoy, A., Barstad, L., Connor, W. E., and Hatcher, L. Absorption of the n-3 eicosapentaenoic and docosahexaenoic acids as ethyl esters and triglycerides by humans. Eritsland J, Amesen H, Gronseth K, et al. 2009;(1):CD006320. But other evidence suggests that taking fish oil does not improve endurance, recovery, heart rate, or exercise duration. Am.J.Psychiatry 2006;163(6):1098-1100. Milte, C. M., Coates, A. M., Buckley, J. D., Hill, A. M., and Howe, P. R. Dose-dependent effects of docosahexaenoic acid-rich fish oil on erythrocyte docosahexaenoic acid and blood lipid levels. 2009;12(5):394-401. Bortolotti, M., Tappy, L., and Schneiter, P. Fish oil supplementation does not alter energy efficiency in healthy males. Arthritis Rheum. 2003Q-0401). Wang, S., Ma, A. Q., Song, S. W., Quan, Q. H., Zhao, X. F., and Zheng, X. H. Fish oil supplementation improves large arterial elasticity in overweight hypertensive patients. Heart disease. Holguin, F., Tellez-Rojo, M. M., Hernandez, M., Cortez, M., Chow, J. C., Watson, J. G., Mannino, D., and Romieu, I. Carrero, J. J., Lopez-Huertas, E., Salmeron, L. M., Baro, L., and Ros, E. Daily supplementation with (n-3) PUFAs, oleic acid, folic acid, and vitamins B-6 and E increases pain-free walking distance and improves risk factors in men with peripheral vascular disease. Mori TA, Bao DQ, Burke V, et al. Marchioli R, Barzi F, Bomba E, and et al. Pathophysiol.Haemost.Thromb. Kiecolt-Glaser, J. K., Belury, M. A., Porter, K., Beversdorf, D. Q., Lemeshow, S., and Glaser, R. Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults. These protective mechanisms include 1. stabilizing blood flow in and around the heart 2. reducing blood triglyceridelevels 3. lowering blood pressure 4. preventing blood clots 5. reducing inflammation. Leaf A. Long-term metabolic effects of n-3 polyunsaturated fatty acids in patients with coronary artery disease. But children who eat fish at least once weekly from the age of 1-2 years seem to have a lower risk of developing eczema. View abstract. View abstract. One study of 90 … J Am Coll Cardiol. Eur.J.Clin.Invest 1999;29(2):100-108. View abstract. View abstract. View abstract. Am J Obstet Gynecol 1996;174:1335-8. Effects of fish oil fatty acids on low density lipoprotein size, oxidizability, and uptake by macrophages. View abstract. Am J Clin Nutr 2007;85(6):1572-1577. View abstract. There is also some evidence that fish oil may help with conditions such as chest pain, liver disease, migraine prevention, gum infections, breast pain, and muscle soreness due to exercise, skin rashes and stomach ulcers. Dodin S, Lemay A, Jacques H, et al. View abstract. New Foundland: ARTS Biomedical Publishers and Distributors;1989. Also, it might be most effective in people with IgA nephropathy who have higher levels of protein in the urine. But early research shows that fish oil supplements might reduce adverse outcomes such as hospital admissions or death in people that already have heart failure. View abstract. Br J Nutr 2008;99(5):1041-1047. View abstract. Effects of n-3 polyunsaturated fatty acid supplementation in pregnancy on maternal and fetal erythrocyte fatty acid composition. 1992;21(4):178-185. Szklarek-Kubicka, M., Fijalkowska-Morawska, J., Zaremba-Drobnik, D., Ucinski, A., Czekalski, S., and Nowicki, M. Effect of intradialytic intravenous administration of omega-3 fatty acids on nutritional status and inflammatory response in hemodialysis patients: a pilot study. Resuscitation 2008;78(3):258-264. View abstract. View abstract. View abstract. J Am Soc Nephrol 1999;10:1772-7. Fish oil supplementation in patients with stable claudication. View abstract. Tur, J. Epilepsy Behav. View abstract. Ng, R. C., Hirata, C. K., Yeung, W., Haller, E., and Finley, P. R. Pharmacologic treatment for postpartum depression: a systematic review. Fish oils seem to decrease blood pressure. Sickle cell disease. Prisco D, Paniccia R, Bandinelli B, et al. Naber, F. B., Oudkerk, Pool M., Teerlink, T., Popp-Snijders, C., Gans, R. O., and Bilo, H. J. Arthritis. Christensen, J. H., Gustenhoff, P., Korup, E., Aaroe, J., Toft, E., Moller, J., Rasmussen, K., Dyerberg, J., and Schmidt, E. B. Kirsch, C. M., Payan, D. G., Wong, M. Y., Dohlman, J. G., Blake, V. A., Petri, M. A., Offenberger, J., Goetzl, E. J., and Gold, W. M. Effect of eicosapentaenoic acid in asthma. Clin.Drug Investig. View abstract. View abstract. View abstract. A placebo-controlled trial. {omega}-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study. Rodriguez, G., Iglesia, I., Bel-Serrat, S., and Moreno, L. A. Engler, M. M., Engler, M. B., Malloy, M., Chiu, E., Besio, D., Paul, S., Stuehlinger, M., Morrow, J., Ridker, P., Rifai, N., and Mietus-Snyder, M. Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study. 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